In episode 492 of The Whole View podcast, Stacy and Dr. Sarah dive deep into the omicron variant of covid-19, including its mutations, where it likely came from (mice!), what makes it so transmissible, its symptoms and how they differ from previous variants, whether or not it’s actually more mild than other variants, how good of a job vaccines are doing at protecting us, and why this variant was able to displace the Delta variant.
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Recommended Reading and Listening
- The Covid-19 mRNA Vaccines
- TWV Podcast Episode 440: Covid-19 Vaccines Part 1 – mRNA Vaccine Technology
- TWV Podcast Episode 441: Covid-19 Vaccines Part 2 – Pfizer/BioNTech vs Moderna
- TWV Podcast Episode 443: Covid-19 Vaccines Part 3 – FAQs
- TWV Podcast Episode 444: Covid-19 Vaccines Part 4 – Myth Busing
- TWV Podcast Episode 454: J&J and AstraZeneca Covid-19 Vaccines
- TWV Podcast Episode 455: Covid-19 Vaccines – Real World Data and Updated Studies
- TWV Podcast Episode 468: The Delta Covid-19 Variant
- TWV Podcast Episode 485: Covid-19 Boosters for Adults
- TWV Podcast Episode 486: Covid-19 Vaccines for Children
Citations
Pronouncing ‘Omicron’: ‘AH-muh-cron’ or ‘Oh-MY-cron’?
COVID Data Tracker Weekly Review | CDC
Understanding the Omicron variant’s mutations – The Washington Post
Evidence for a mouse origin of the SARS-CoV-2 Omicron variant
Omicron variant and booster COVID-19 vaccines
SARS-CoV-2 Omicron VOC Transmission in Danish Households
Initial Assessment of SARS-CoV-2 Omicron Variant in Exhaled Breath Aerosol
Infectious viral load in unvaccinated and vaccinated patients infected with SARS-CoV-2 WT, Delta and Omicron | medRxiv
SARS-CoV-2 Omicron spike mediated immune escape, infectivity and cell-cell fusion | bioRxiv
Eurosurveillance | Outbreak caused by the SARS-CoV-2 Omicron variant in Norway, November to December 2021
Investigation of a SARS-CoV-2 B.1.1.529 (Omicron) Variant Cluster — Nebraska, November–December 2021 | MMWR
If you’ve been exposed to the coronavirus – Harvard Health
SARS-CoV-2 Transmission From People Without COVID-19 Symptoms
Structural models of SARS-CoV-2 Omicron variant in complex with ACE2 receptor or antibodies suggest altered binding interfaces | bioRxiv
High Rate of Asymptomatic Carriage Associated with Variant Strain Omicron | medRxiv
HKUMed finds Omicron SARS-CoV-2 can infect faster and better than Delta in human bronchus but with less severe infection in lung
What we know about the Omicron COVID-19 variant so far
Early assessment of the clinical severity of the SARS-CoV-2 Omicron variant in South Africa | medRxiv
Early signals of significantly increased vaccine breakthrough, decreased hospitalization rates, and less severe disease in patients with COVID-19 caused by the Omicron variant of SARS-CoV-2 in Houston, Texas | medRxiv
Clinical outcomes among patients infected with Omicron (B.1.1.529) SARS-CoV-2 variant in southern California
Outcomes of laboratory-confirmed SARS-CoV-2 infection in the Omicron-driven fourth wave compared with previous waves in the Western Cape Province, South Africa | medRxiv
SARS-CoV-2 variants of concern and variants under investigation
Severity of Omicron variant of concern and vaccine effectiveness against symptomatic disease: national cohort with nested test negative design study in Scotland — University of Edinburgh Research Explorer
mRNA-based COVID-19 vaccine boosters induce neutralizing immunity against SARS-CoV-2 Omicron variant – ScienceDirect
Effectiveness of 3 doses of COVID-19 vaccines against symptomatic COVID-19 and hospitalization in adults aged 65 years and older
Protection afforded by prior infection against SARS-CoV-2 reinfection with the Omicron variant
Omicron infection enhances neutralizing immunity against the Delta variant
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